Type of sarcoma: 
Bristol, Newcastle, Leeds, London, Manchester, Oxford, Liverpool, Glasgow, Aberdeen, Birmingham, Nottingham
Full Title: Multi-arm, multi-stage, randomised phase II/phase II open label multi-centre randomised controlled trial of chemotherapy for the treatment of recurrent and primary refractory Ewing's. 

Age: 2-50
Status: Open
Phase: Phase 2

If you have Ewing's sarcoma which cannot be removed by surgery or has returned after initial treatment, you may be given chemotherapy. This study compares four different chemotherapy treatments: 
  • topotecan and cyclophosphamide (TC)
  • irinotecan and temozolomide (IT) 
  • gemcitabine and docetaxel (GD)
  • high-dose ifosfamide (IFOS)