Professor Adrienne Flanagan
Wednesday, July 11, 2018

How will sarcoma be treated in the future? The answer may be hidden in our genes.

Over the last couple of years, people with rare cancers and their families have given samples of their genes to a landmark research project called the 100,000 Genomes Project. Up to 500 of these genomes are from people with sarcoma.  

This groundbreaking project opens up a new area of medical research called Genomics. Genomics can predict how well a patient will respond to a treatment or find one that will work best for them. Using Genomics, we could find out if certain cancers will respond to radiotherapy or not. This could, for example, mean fewer radiotherapy sessions for a patient.

Sarcoma UK is hugely excited by what Genomics can do. That’s why we are launching our transformational Genomic Research Programme with the aim of bringing a step change in sarcoma research. We will award £250,000 to one project that brings together the best researchers using the latest technologies using the sarcoma samples collected and analysed in the 100,000 Genomes Project. 

We have listened to our researchers at our Sarcoma Research Symposium and we have launched this programme to bring researchers together to work on a transformational idea that will bring change and improved outcomes for sarcoma patients.

'This is a key moment for sarcoma research', says Sarah McDonald, Director of Research. 'The opportunity presented by the high quality samples, linked to clinical data and whole genome sequencing undertaken by the 100,000 Genomes project is a once in a lifetime event. By investing in this forefront, groundbreaking research, we will bring about transformational change in sarcoma research'.

We are inviting applications from teams to share their vision for what the sarcoma samples in the 100,000 Genomes Project could do to transform research and outline a research project to start working towards this.

Find out more about the 100,000 Genomes Project.

Apply for funding under the new Genomic Research Programme.


(Image of Professor Adrienne Flanaganlead researcher for the sarcoma element of the 100,000 Genomes Project.)